Recombinant SSTR2 anticorps
-
- Antigène Voir toutes SSTR2 Anticorps
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
- Type d'anticorp
- Recombinant Antibody
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp SSTR2 est non-conjugé
-
Application
- ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Affinity-chromatography
- Immunogène
- A synthesized peptide derived from human Somatostatin Receptor 2
- Clone
- 1C3
- Isotype
- IgG
- Top Product
- Discover our top product SSTR2 Anticorps primaire
-
-
- Indications d'application
- Recommended dilution: IHC:1:50-1:200,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
- Autre désignation
- SSTR2 (SSTR2 Produits)
- Synonymes
- anticorps Smstr2, anticorps SSTR-2, anticorps Smstr-2, anticorps sst2, anticorps SS2R, anticorps SSTR2, anticorps MGC80373, anticorps somatostatin receptor 2, anticorps somatostatin receptor 2 L homeolog, anticorps SSTR2, anticorps Sstr2, anticorps sstr2.L
- Sujet
-
Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
Aliases: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1), SSTR2
- UniProt
- P30874
-