Recombinant TACC3 anticorps

N° du produit ABIN7127834

Détail du produit anti-TACC3 anticorps

Antigène: TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TACC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human TACC3

Clone: 10G7

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TACC3

Antigène: TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))

Autre désignation: TACC3 (TACC3 Produits)

Synonymes: anticorps Aint, anticorps C86661, anticorps Eric1, anticorps ERIC-1, anticorps ERIC1, anticorps maskin, anticorps masking, anticorps xmaskin, anticorps transforming, acidic coiled-coil containing protein 3, anticorps transforming acidic coiled-coil containing protein 3, anticorps transforming acidic coiled-coil containing protein 3 S homeolog, anticorps Tacc3, anticorps TACC3, anticorps tacc3.S

Sujet:

Background: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).

Aliases: Transforming acidic coiled-coil-containing protein 3 (ERIC-1), TACC3, ERIC1

UniProt: Q9Y6A5

Pathways: Maintenance of Protein Location