PHLPP1 anticorps

N° du produit ABIN7130610

Détail du produit anti-PHLPP1 anticorps

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHLPP1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human PHLPP1

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PHLPP1

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Autre désignation: PHLPP1 (PHLPP1 Produits)

Synonymes: anticorps PHLPP, anticorps PLEKHE1, anticorps SCOP, anticorps AI836256, anticorps Phlpp, anticorps Plekhe1, anticorps mKIAA0606, anticorps Scop, anticorps PH domain and leucine rich repeat protein phosphatase 1, anticorps PHLPP1, anticorps phlpp1, anticorps Phlpp1

Sujet:

Background: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Aliases: hSCOP antibody, KIAA0606 antibody, PH domain and leucine rich repeat protein phosphatase antibody, PH domain leucine rich repeat containing protein phosphatase antibody, PH domain leucine rich repeat protein phosphatase antibody, PH domain leucine-rich repeat-containing protein phosphatase 1 antibody, PH domain-containing family E member 1 antibody, PHLP1_HUMAN antibody, PHLPP antibody, Phlpp1 antibody, Pleckstrin homology domain containing family E (with leucine rich repeats) member 1 antibody, Pleckstrin homology domain containing family E protein 1 antibody, Pleckstrin homology domain-containing family E member 1 antibody, PLEKHE 1 protein antibody, PLEKHE1 antibody, SCN circadian oscillatory protein antibody, SCOP antibody, Suprachiasmatic nucleus circadian oscillatory protein antibody, Suprachiasmatic nucleus circadian protein antibody

UniProt: O60346

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway