TWIST2 anticorps

N° du produit ABIN7138153

Détail du produit anti-TWIST2 anticorps

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWIST2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TWIST2

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Autre désignation: TWIST2 (TWIST2 Produits)

Synonymes: anticorps TWIST2, anticorps DERMO1, anticorps FFDD3, anticorps SETLSS, anticorps bHLHa39, anticorps Dermo1, anticorps CDERMO-1, anticorps twist family bHLH transcription factor 2, anticorps twist basic helix-loop-helix transcription factor 2, anticorps TWIST2, anticorps Twist2

Sujet:

Background:

Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000)

Aliases: bHLHa39 antibody, Class A basic helix-loop-helix protein 39 antibody, Dermis expressed protein 1 antibody, Dermis-expressed protein 1 antibody, DERMO 1 antibody, Dermo-1 antibody, DERMO1 antibody, MGC117334 antibody, Twist 2 antibody, Twist homolog 2 (Drosophila) antibody, Twist homolog 2 antibody, Twist related bHLH protein Dermo1 antibody, Twist related protein 2 antibody, Twist-related protein 2 antibody, Twist2 antibody, TWST2_HUMAN antibody

UniProt: Q8WVJ9

Pathways: Chromatin Binding