TAL1 anticorps (pSer122)

N° du produit ABIN7138416

Détail du produit anti-TAL1 anticorps

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Épitope: pSer122

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TAL1

Antigène: TAL1 (T-Cell Acute Lymphocytic Leukemia 1 (TAL1))

Autre désignation: TAL1 (TAL1 Produits)

Synonymes: anticorps SCL/tal-1, anticorps Scl, anticorps bHLHa17, anticorps tal-1, anticorps SCL, anticorps TCL5, anticorps scl, anticorps tcl5, anticorps SCL-alpha, anticorps SCL-beta, anticorps scl/tal1, anticorps zgc:85605, anticorps T cell acute lymphocytic leukemia 1, anticorps TAL bHLH transcription factor 1, erythroid differentiation factor, anticorps T-cell acute lymphocytic leukemia 1 S homeolog, anticorps T-cell acute lymphocytic leukemia 1, anticorps Tal1, anticorps TAL1, anticorps tal1.S, anticorps tal1

Sujet:

Background:

TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Aplan P.D., Mol. Cell. Biol. 10:6426-6435(1990).
Gregory S.G., Nature 441:315-321(2006).
Chen Q., J. Exp. Med. 172:1403-1408(1990).

Aliases: bHLHa17 antibody, Class A basic helix-loop-helix protein 17 antibody, OTTHUMP00000009563 antibody, OTTHUMP00000009564 antibody, SCL antibody, STEM CELL LEUKEMIA HEMATOPOIETIC TRANSCRIPTION FACTOR antibody, Stem cell protein antibody, T cell acute lymphocytic leukemia 1 antibody, T cell acute lymphocytic leukemia 1 protein antibody, T cell acute lymphocytic leukemia 1 protein antibody, T cell leukemia/lymphoma 5 protein antibody, T-cell acute lymphocytic leukemia protein 1 antibody, T-cell leukemia/lymphoma protein 5 antibody, Tal 1 antibody, Tal 1 product antibody, TAL 1 protein antibody, TAL bHLH transcription factor 1 erythroid differentiation factor antibody, TAL-1 antibody, tal1 antibody, TAL1_HUMAN antibody, TCL 5 antibody, TCL5 antibody

UniProt: P17542

Pathways: Stem Cell Maintenance