PAK2 anticorps (pSer197)

N° du produit ABIN7138464

Détail du produit anti-PAK2 anticorps

Antigène: PAK2 (P21-Activated Kinase 2 (PAK2))

Épitope: pSer197

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 197(T-R-S(p)-V-I) derived from Human PAK2.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PAK2

Antigène: PAK2 (P21-Activated Kinase 2 (PAK2))

Autre désignation: PAK2 (PAK2 Produits)

Synonymes: anticorps PAK65, anticorps PAKgamma, anticorps gamma-PAK, anticorps 5330420P17Rik, anticorps A130002K10Rik, anticorps AI836325, anticorps D16Ertd269e, anticorps PAK-2, anticorps mKIAA4182, anticorps pak2, anticorps cb422, anticorps kinase, anticorps zgc:91798, anticorps wu:fb71h01, anticorps si:dz198m22.1, anticorps pak65, anticorps pakgamma, anticorps PAKI, anticorps Pak3, anticorps CH73-159L23.1, anticorps wu:fc52b03, anticorps zgc:113857, anticorps p21 (RAC1) activated kinase 2, anticorps p21 protein (Cdc42/Rac)-activated kinase 2, anticorps p21 protein (Cdc42/Rac)-activated kinase 2a, anticorps p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog, anticorps p21 protein (Cdc42/Rac)-activated kinase 2b, anticorps PAK2, anticorps Pak2, anticorps pak2a, anticorps pak2.S, anticorps pak2b

Sujet:

Background:

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Martin G.A., EMBO J. 14:1970-1978(1995).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Olsen J.V., Cell 127:635-648(2006).

Aliases: C-t-PAK2 antibody, CB422 antibody, EC 2.7.11.1 antibody, Gamma PAK antibody, Gamma-PAK antibody, hPAK65 antibody, Kinase antibody, p21 (CDKN1A) activated kinase 2 antibody, p21 (CDKN1A)-activated kinase 2a antibody, p21 activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein Cdc42 Rac activated kinase 2 antibody, p21-activated kinase 2 antibody, p21-activated kinase, 65-KD antibody, p21-activated protein kinase I antibody, p21CDKN1A activated kinase 2 antibody, p27 antibody, p34 antibody, p58 antibody, p65PAK antibody, PAK 2 antibody, PAK-2 antibody, PAK-2p34 antibody, Pak2 antibody, PAK2_HUMAN antibody, PAK65 antibody, PAKgamma antibody, S6 H4 kinase antibody, S6/H4 kinase antibody, Serine threonine protein kinase PAK 2 antibody, Serine/threonine protein kinase PAK 2 antibody

UniProt: Q13177

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha