CTBP1 anticorps (pSer422)

N° du produit ABIN7138613

Détail du produit anti-CTBP1 anticorps

Antigène: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Épitope: pSer422

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTBP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 422(A-P-S(p)-P-G) derived from Human CtBP1.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CTBP1

Antigène: CTBP1 (C-terminal Binding Protein 1 (CTBP1))

Autre désignation: CTBP1 (CTBP1 Produits)

Sujet:

Background:

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Aliases: BARS antibody, brefeldin A- ribosylated substrate antibody, C terminal binding protein 1 antibody, C-terminal-binding protein 1 antibody, CTBP antibody, CtBP1 antibody, CTBP1_HUMAN antibody, MGC104684 antibody

UniProt: Q13363

Pathways: Retinoic Acid Receptor Signaling Pathway