VAV3 anticorps (pTyr173)

N° du produit ABIN7138947

Détail du produit anti-VAV3 anticorps

Antigène: VAV3 (Vav 3 Oncogene (VAV3))

Épitope: pTyr173

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAV3 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 173 (E-V-Y(p)-E-D) derived from Human VAV3.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur VAV3

Antigène: VAV3 (Vav 3 Oncogene (VAV3))

Autre désignation: VAV3 (VAV3 Produits)

Synonymes: anticorps RGD1565941, anticorps A530094I06Rik, anticorps AA986410, anticorps Idd18.1, anticorps vav guanine nucleotide exchange factor 3, anticorps vav 3 guanine nucleotide exchange factor, anticorps vav 3 oncogene, anticorps VAV3, anticorps Vav3

Sujet:

Background:

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Trenkle T., Nucleic Acids Res. 26:3883-3891(1998).
Movilla N., Mol. Cell. Biol. 19:7870-7885(1999).

Aliases: FLJ40431 antibody, Guanine nucleotide exchange factor VAV3 antibody, Protein vav 3 antibody, Protein vav3 antibody, RGD1565941 antibody, VAV 3 antibody, Vav 3 guanine nucleotide exchange factor antibody, VAV 3 oncogene antibody, VAV 3 protein antibody, VAV-3 antibody, Vav3 antibody, VAV3 oncogene antibody, VAV3 protein antibody, VAV3_HUMAN antibody

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway