HCK anticorps (pTyr521)

N° du produit ABIN7139019

Détail du produit anti-HCK anticorps

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Épitope: pTyr521

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCK est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 521(E-S-Q(p)-Y-Q) derived from Human HCK .

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: HCK (HCK Produits)

Synonymes: anticorps laloo, anticorps HCK, anticorps MGC107870, anticorps JTK9, anticorps p59Hck, anticorps p61Hck, anticorps AI849071, anticorps Bmk, anticorps Hctk, anticorps p56Hck, anticorps HCK proto-oncogene, Src family tyrosine kinase L homeolog, anticorps HCK proto-oncogene, Src family tyrosine kinase, anticorps hemopoietic cell kinase, anticorps hck.L, anticorps HCK, anticorps hck, anticorps Hck

Sujet:

Background:

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Quintrell N., Mol. Cell. Biol. 7:2267-2275(1987) [PubMed: 3496523].
Ziegler S.F.,Mol. Cell. Biol. 7:2276-2285(1987) [PubMed: 3453117].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].

Aliases: Bmk antibody, Hck 1 antibody, Hck antibody, HCK_HUMAN antibody, Hemopoietic cell kinase antibody, JTK9 antibody, p59-HCK/p60-HCK antibody, p59Hck antibody, p59HCK/p60HCK antibody, p61Hck antibody, Tyrosine protein kinase HCK antibody, Tyrosine-protein kinase HCK antibody

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling