IgG3 anticorps (AA 312-324) (Biotin)
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- Antigène Voir toutes IgG3 Anticorps
- IgG3
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Épitope
- AA 312-324
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IgG3 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA)
- Isotype
- IgG
- Top Product
- Discover our top product IgG3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- IgG3
- Autre désignation
- IGHG3 (IgG3 Produits)
- Synonymes
- anticorps IgG3, anticorps Immunoglobulin heavy constant gamma 3, anticorps immunoglobulin heavy constant gamma 3 (G3m marker), anticorps Ighg3, anticorps IGHG3
- Classe de substances
- Antibody
- Sujet
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Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Aliases: IGHG3Immunoglobulin heavy constant gamma 3 antibody, HDC antibody, Heavy chain disease protein antibody, Ig gamma-3 chain C region antibody
- UniProt
- P01860
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