MDFIC anticorps (AA 35-53)

N° du produit ABIN7139928

Détail du produit anti-MDFIC anticorps

Antigène: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Épitope: AA 35-53

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDFIC est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MDFIC

Antigène: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Autre désignation: MDFIC (MDFIC Produits)

Synonymes: anticorps HIC, anticorps Kdt1, anticorps Mdfid, anticorps MyoD family inhibitor domain containing, anticorps MyoD family inhibitor domain containing S homeolog, anticorps MDFIC, anticorps Mdfic, anticorps mdfic.S

Sujet:

Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Aliases: MDFIC antibody, MyoD family inhibitor domain-containing protein antibody, I-mfa domain-containing protein antibody, hIC antibody

UniProt: Q9P1T7