LRP1 anticorps (AA 3924-3942)

N° du produit ABIN7140070

Détail du produit anti-LRP1 anticorps

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Épitope: AA 3924-3942

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Peptide sequence from Human Prolow-density lipoprotein receptor-related protein 1 protein (3924-3942AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LRP1

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Autre désignation: LRP1 (LRP1 Produits)

Synonymes: anticorps A2MR, anticorps APOER, anticorps APR, anticorps CD91, anticorps IGFBP3R, anticorps LRP, anticorps LRP1A, anticorps TGFBR5, anticorps A2mr, anticorps AI316852, anticorps Lrp, anticorps LRP-1, anticorps LDL receptor related protein 1, anticorps prolow-density lipoprotein receptor-related protein 1, anticorps low density lipoprotein receptor-related protein 1, anticorps LRP1, anticorps Lrp1, anticorps LOC100414789

Sujet:

Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:11907044, PubMed:12888553, PubMed:12713657). Acts as an alpha-2-macroglobulin receptor (PubMed:26142438).

Aliases: A2MR antibody, Alpha 2 macroglobulin receptor antibody, alpha 2MR antibody, Alpha-2-macroglobulin receptor antibody, APOER antibody, Apolipoprotein E receptor antibody, APR antibody, CD 91 antibody, CD91 antibody, CD91 antigen antibody, IGFBP3R antibody, LDL receptor related protein 1 antibody, Low density lipoprotein receptor related protein 1 antibody, Low density lipoprotein related protein 1 antibody, Low-density lipoprotein receptor-related protein 1 intracellular domain antibody, LRP 1 antibody, LRP 515 antibody, LRP 85 antibody, LRP antibody, LRP ICD antibody, LRP-1 antibody, LRP-515 antibody, LRP-85 antibody, Lrp1 antibody, LRP1 protein antibody, LRP1_HUMAN antibody, LRP1A antibody, LRP515 antibody, LRP85 antibody, LRPICD antibody, MGC88725 antibody, Prolow density lipoprotein receptor related protein 1 antibody, TbetaR V/LRP 1/IGFBP 3 receptor antibody, TbetaRV/LRP1/IGFBP3 receptor antibody, TGFBR 5 antibody, TGFBR5 antibody, Type V tgf beta receptor antibody

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling