RTN4RL2 anticorps (AA 355-372)

N° du produit ABIN7140114

Détail du produit anti-RTN4RL2 anticorps

Antigène: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Épitope: AA 355-372

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTN4RL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Peptide sequence from Human Reticulon-4 receptor-like 2 protein (355-372AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RTN4RL2

Antigène: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Autre désignation: RTN4RL2 (RTN4RL2 Produits)

Synonymes: anticorps NGRH1, anticorps NgR2, anticorps RTN4RL2, anticorps Ngr2, anticorps Ngrh1, anticorps Ngrl3, anticorps NgRH1b, anticorps rtn4rl2, anticorps NgRH1a, anticorps reticulon 4 receptor like 2, anticorps reticulon 4 receptor-like 2, anticorps reticulon 4 receptor-like 2b, anticorps reticulon 4 receptor-like 2 a, anticorps RTN4RL2, anticorps Rtn4rl2, anticorps rtn4rl2b, anticorps rtn4rl2a

Sujet:

Background: Cell surface receptor that plays a functionally redundant role in the inhibition of neurite outgrowth mediated by MAG (By similarity). Plays a functionally redundant role in postnatal brain development. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Does not seem to play a significant role in regulating axon regeneration in the adult central nervous system. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed: 22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed: 22325200).

Aliases: RTN4RL2 antibody, NGRH1 antibody, NGRL3 antibody, Reticulon-4 receptor-like 2 antibody, Nogo receptor-like 3 antibody, Nogo-66 receptor homolog 1 antibody, Nogo-66 receptor-related protein 2 antibody, NgR2 antibody

UniProt: Q86UN3