BRAP anticorps

N° du produit ABIN7140299

Détail du produit anti-BRAP anticorps

Antigène: BRAP (BRCA1 Associated Protein (BRAP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BRAP est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: Affinity purified

Immunogène: Purified recombinant human BRAP protein fragments expressed in E.coli.

Isotype: IgG1, IgG1 kappa

Information d'application

Indications d'application: Recommended dilution:WB:1:500-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BRAP

Antigène: BRAP (BRCA1 Associated Protein (BRAP))

Autre désignation: BRAP (BRAP Produits)

Synonymes: anticorps imp, anticorps MGC68778, anticorps zgc:92894, anticorps BRAP, anticorps BRAP2, anticorps IMP, anticorps RNF52, anticorps 3010002G07Rik, anticorps BRCA1 associated protein S homeolog, anticorps BRCA1 associated protein, anticorps BRCA1-associated protein, anticorps brca1-associated protein, anticorps brap.S, anticorps brap, anticorps BRAP, anticorps NAEGRDRAFT_81654, anticorps CC1G_00971, anticorps CpipJ_CPIJ003557, anticorps Tsp_05101, anticorps LOC100282389, anticorps Brap

Sujet:

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Aliases: 3010002G07Rik, BRAP2, BRCA1 associated protein, EC 6.3.2., Galectin 2 binding protein, IMP, Impedes mitogenic signal propagation, Renal carcinoma antigen NY REN 63, RING finger protein 52, RNF52, zgc:92894.

UniProt: Q7Z569