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IFNK anticorps (AA 24-195) (FITC)

IFNK Reactivité: Boeuf (Vache) Hôte: Lapin Polyclonal FITC
N° du produit ABIN7140832
  • Antigène Tous les produits IFNK
    IFNK (Interferon, kappa (IFNK))
    Épitope
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-195
    Reactivité
    • 19
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Boeuf (Vache)
    Hôte
    • 18
    • 5
    • 1
    Lapin
    Clonalité
    • 22
    • 2
    Polyclonal
    Conjugué
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IFNK est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Boeuf (Vache)
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Bovine Interferon tau-1 protein (24-195AA)
    Isotype
    IgG
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    IFNK (Interferon, kappa (IFNK))
    Autre désignation
    IFNT1 (IFNK Produits)
    Synonymes
    anticorps IFNK, anticorps IFNT1, anticorps INFE1, anticorps RP11-27J8.1, anticorps interferon kappa, anticorps IFNK, anticorps Ifnk
    Sujet

    Background: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.

    Aliases: IFNT1 antibody, Interferon tau-1 antibody, IFN-tau-1 antibody, Antiluteolysin antibody, Trophoblast antiluteolytic protein antibody, Trophoblast protein 1 antibody, TP-1 antibody, Trophoblastin antibody

    UniProt
    P15696
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