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RABAC1 anticorps (AA 16-299)

RABAC1 Reactivité: Candida albicans ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7140908
  • Antigène Voir toutes RABAC1 Anticorps
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    Épitope
    • 3
    • 1
    • 1
    • 1
    AA 16-299
    Reactivité
    • 5
    • 3
    • 1
    • 1
    Candida albicans
    Hôte
    • 7
    • 1
    Lapin
    Clonalité
    • 7
    • 1
    Polyclonal
    Conjugué
    • 5
    • 1
    • 1
    • 1
    Cet anticorp RABAC1 est non-conjugé
    Application
    • 6
    • 5
    • 2
    ELISA, Western Blotting (WB)
     Réactivité croisée
    Candida albicans
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)
    Isotype
    IgG
    Top Product
    Discover our top product RABAC1 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))
    Autre désignation
    PRA1 (RABAC1 Produits)
    Synonymes
    anticorps PRA1, anticorps PRAF1, anticorps YIP3, anticorps 2310040I06Rik, anticorps Gbpap1, anticorps prenylin, anticorps Pra1, anticorps wu:fe26d12, anticorps zgc:86749, anticorps MGC81207, anticorps pra1, anticorps yip3, anticorps praf1, anticorps MGC146421, anticorps F22K20.5, anticorps F22K20_5, anticorps Rab acceptor 1, anticorps Rab acceptor 1 (prenylated), anticorps Rab acceptor 1 (prenylated) S homeolog, anticorps Rab acceptor 1 (prenylated) L homeolog, anticorps Regulator of chromosome condensation (RCC1) family with FYVE zinc finger domain-containing protein, anticorps RABAC1, anticorps Rabac1, anticorps rabac1, anticorps rabac1.S, anticorps rabac1.L, anticorps PRAF1
    Sujet

    Background: Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.

    Aliases: PRA1 antibody, FBP1 antibody, CAALFM_C406980WA antibody, CaO19.10623 antibody, CaO19.3111 antibody, pH -regulated antigen PRA1 antibody, 58 kDa fibrinogen-binding mannoprotein antibody

    UniProt
    P87020
    Pathways
    Chromatin Binding
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