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CD14 anticorps

CD14 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 1A3B6 unconjugated
N° du produit ABIN7140933
  • Antigène Voir toutes CD14 Anticorps
    CD14
    Reactivité
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    Souris
    Clonalité
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    Monoclonal
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    Cet anticorp CD14 est non-conjugé
    Application
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    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Protein G purified
    Immunogène
    Recombinant CD14 Protein
    Clone
    1A3B6
    Isotype
    IgG2b
    Top Product
    Discover our top product CD14 Anticorps primaire
  • Indications d'application
    Recommended dilution:IHC:1:50-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    CD14
    Autre désignation
    CD14 (CD14 Produits)
    Synonymes
    anticorps CD14 molecule, anticorps CD14 antigen, anticorps CD14, anticorps Cd14
    Sujet

    Background: As a component of the innate immune system, the cell surface glycoprotein CD14 is a myelomonocytic differentiation antigen preferentially expressed on monocytes, macrophages, and activated granulocytes. CD14 exists as two forms, either anchored into the membrane by a GPI-anchor tail (mCD14) or present as a soluble form (sCD14) in normal serum and body fluids. CD14 was first described as a pattern recognition receptor for lipopolysaccharide (LPS) and a variety of ligands derived from different microbial sources, along with the co-receptors Toll-like receptor TLR 4 and MD-2. The binding of CD14 and LPS depends on the presence and catalytic activity of lipopolysaccharide-binding protein (LBP). Besides its endotoxin signaling function, CD14 has been proposed to be involved in various biological processes, including transportation of other lipids, cell-cell interaction during different immune responses, as well as recognition of apoptotic cells. Multiple transcript variants resulting from alternative splicing encode the same isoform of CD14.

    Aliases: CD14, CD14 Molecule

    UniProt
    P08571
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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