PLCD4 anticorps (AA 1-290)

N° du produit ABIN7142053

Détail du produit anti-PLCD4 anticorps

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Épitope: AA 1-290

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCD4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein (1-290AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLCD4

Antigène: PLCD4 (Phospholipase C, delta 4 (PLCD4))

Autre désignation: PLCD4 (PLCD4 Produits)

Synonymes: anticorps PLCD4, anticorps PLCL3, anticorps si:dkeyp-84a8.7, anticorps 4921507K24Rik, anticorps phospholipase C eta 1, anticorps phospholipase C delta 4, anticorps phospholipase C, delta 4a, anticorps phospholipase C, delta 4, anticorps phospholipase C delta 4 L homeolog, anticorps PLCH1, anticorps PLCD4, anticorps plcd4a, anticorps plcd4, anticorps Plcd4, anticorps plcd4.L

Sujet:

Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase delta 4 antibody, 1-phosphatidylinositol 4 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase delta-4 antibody, hPLCD4 antibody, MGC12837 antibody, Phosphoinositide phospholipase C delta 4 antibody, Phosphoinositide phospholipase C-delta-4 antibody, Phospholipase C delta 4 antibody, Phospholipase C-delta-4 antibody, PLC delta 4 antibody, PLC delta4 antibody, PLC-delta-4 antibody, PLCD4 antibody, PLCD4_HUMAN antibody

UniProt: Q9BRC7

Pathways: Inositol Metabolic Process