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RNASEL anticorps (AA 330-741) (HRP)

RNASEL Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7142133
  • Antigène Voir toutes RNASEL Anticorps
    RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
    Épitope
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 330-741
    Reactivité
    • 19
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 28
    • 4
    • 1
    Lapin
    Clonalité
    • 30
    • 3
    Polyclonal
    Conjugué
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    Cet anticorp RNASEL est conjugé à/à la HRP
    Application
    • 26
    • 24
    • 5
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human 2-5A-dependent ribonuclease protein (330-741AA)
    Isotype
    IgG
    Top Product
    Discover our top product RNASEL Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
    Autre désignation
    RNASEL (RNASEL Produits)
    Synonymes
    anticorps E230029I04Rik, anticorps PRCA1, anticorps RNS4, anticorps ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent), anticorps ribonuclease L, anticorps Rnasel, anticorps RNASEL
    Sujet

    Background: Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. Might play a central role in the regulation of mRNA turnover.

    Aliases: 2 5A dependent ribonuclease antibody, 2 5A dependent RNase antibody, 2' 5' oligoisoadenylate synthetase dependent antibody, 2-5A-dependent ribonuclease antibody, 2-5A-dependent RNase antibody, DKFZp781D08126 antibody, Interferon induced 2 5A dependent RNase antibody, MGC104972 antibody, MGC133329 antibody, PRCA 1 antibody, PRCA1 antibody, Ribonuclease 4 antibody, Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) antibody, Ribonuclease L antibody, Ribonuclease4 antibody, RibonucleaseL antibody, RN5A_HUMAN antibody, RNase L antibody, Rnasel antibody, RNS 4 antibody, RNS4 antibody

    UniProt
    Q05823
    Pathways
    Hepatitis C
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