ERI1 anticorps (AA 2-66) (Biotin)

N° du produit ABIN7142340

Détail du produit anti-ERI1 anticorps (Biotin)

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Épitope: AA 2-66

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERI1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human 3\'-5\' exoribonuclease 1 protein (2-66AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERI1

Antigène: ERI1 (Exoribonuclease 1 (ERI1))

Autre désignation: ERI1 (ERI1 Produits)

Synonymes: anticorps THEX1, anticorps thex1, anticorps zgc:110635, anticorps hexo, anticorps Eri-1, anticorps 3'HEXO, anticorps HEXO, anticorps 3'hexo, anticorps 3110010F15Rik, anticorps Thex1, anticorps eri-1, anticorps RGD1308378, anticorps exoribonuclease 1, anticorps three prime repair exonuclease 1, anticorps exoribonuclease 1 L homeolog, anticorps 3'-5' exonuclease eri-1, anticorps ERI1, anticorps CpipJ_CPIJ003945, anticorps eri1, anticorps eri1.L, anticorps Eri1, anticorps eri-1

Sujet:

Background: RNA exonuclease that binds to the 3\'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2\' and 3\'-hydroxyl groups at the last nucleotide of the histone 3\'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3\'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5\'-ACCCA-3\' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3\'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.

Aliases: 3' 5' exonuclease ERI 1 antibody, 3' 5' exonuclease ERI1 antibody, 3' EXO antibody, 3' exoribonuclease antibody, 3' HEXO antibody, 3' histone mRNA exonuclease 1 antibody, 3''-5'' exonuclease eri1 antibody, 3''-5'' exoribonuclease 1 antibody, 3'EXO antibody, 3'HEXO antibody, ERI 1 antibody, Eri 1 homolog antibody, Eri-1 homolog antibody, eri1 antibody, Eri1 homolog antibody, ERI1_HUMAN antibody, HEXO antibody, Histone mRNA 3' end specific exonuclease antibody, Histone mRNA 3' end specific exoribonuclease antibody, Histone mRNA 3''-end-specific exoribonuclease antibody, Histone mRNA 3''-exonuclease 1 antibody, MGC35395 antibody, Protein 3''hExo antibody, THEX 1 antibody, THEX1 antibody, Three prime histone mRNA exonuclease 1 antibody

UniProt: Q8IV48