ARPC3 anticorps (AA 2-175)
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- Antigène Voir toutes ARPC3 Anticorps
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
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Épitope
- AA 2-175
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARPC3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))
- Autre désignation
- ARPC3 (ARPC3 Produits)
- Synonymes
- anticorps ARC21, anticorps p21-Arc, anticorps 1110006A04Rik, anticorps 21kDa, anticorps AA408672, anticorps AI788639, anticorps p21-Ar, anticorps p21Arc, anticorps arc21, anticorps p21-arc, anticorps zgc:86828, anticorps actin related protein 2/3 complex subunit 3, anticorps actin related protein 2/3 complex, subunit 3, anticorps actin related protein 2/3 complex subunit 3 L homeolog, anticorps actin related protein 2/3 complex, subunit 3, 21kDa, anticorps actin related protein 2/3 complex subunit 3 pseudogene, anticorps actin-related protein 2/3 complex subunit 3, anticorps actin-related protein 2/3 complex subunit 3 pseudogene, anticorps ARPC3, anticorps Arpc3, anticorps arpc3.L, anticorps LOC738738, anticorps arpc3, anticorps LOC100036831, anticorps LOC100341254
- Sujet
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Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody
- UniProt
- O15145
- Pathways
- Signalisation RTK, Regulation of Actin Filament Polymerization
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