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MOCS3 anticorps (AA 271-460)

MOCS3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7143362
  • Antigène Voir toutes MOCS3 Anticorps
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Épitope
    • 14
    • 7
    • 6
    • 4
    • 1
    AA 271-460
    Reactivité
    • 19
    • 17
    • 2
    Humain
    Hôte
    • 26
    • 5
    Lapin
    Clonalité
    • 29
    • 2
    Polyclonal
    Conjugué
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp MOCS3 est non-conjugé
    Application
    • 27
    • 18
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))
    Autre désignation
    MOCS3 (MOCS3 Produits)
    Synonymes
    anticorps MOCS3, anticorps DDBDRAFT_0189692, anticorps DDBDRAFT_0267172, anticorps DDB_0189692, anticorps DDB_0267172, anticorps UBA4, anticorps 1700020H17Rik, anticorps Uba4, anticorps zgc:55696, anticorps uba4, anticorps molybdenum cofactor synthesis 3, anticorps molybdenum cofactor synthesis 3 L homeolog, anticorps MOCS3, anticorps mocs3, anticorps Mocs3, anticorps mocs3.L
    Sujet

    Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

    Aliases: Adenylyltransferase MOCS3 antibody, dJ914P20.3 antibody, MGC9252 antibody, MOCS 3 antibody, MOCS3 antibody, MOCS3_HUMAN antibody, Molybdenum cofactor synthesis 3 antibody, Molybdenum cofactor synthesis protein 3 antibody, Molybdopterin synthase sulfurylase antibody, Molybdopterin-synthase sulfurtransferase antibody, MPT synthase sulfurylase antibody, Sulfur carrier protein MOCS2A adenylyltransferase antibody, Sulfur carrier protein MOCS2A sulfurtransferase antibody, Sulfurtransferase MOCS3 antibody, UBA 4 antibody, UBA4 ubiquitin activating enzyme E1 homolog antibody, UBA4 antibody

    UniProt
    O95396
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