ARF1 anticorps (AA 2-181)

N° du produit ABIN7143442

Détail du produit anti-ARF1 anticorps

Antigène: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Épitope: AA 2-181

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ADP-ribosylation factor 1 protein (2-181AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARF1

Antigène: ARF1 (ADP-Ribosylation Factor 1 (ARF1))

Autre désignation: ARF1 (ARF1 Produits)

Synonymes: anticorps wu:fb33e02, anticorps wu:fb78h01, anticorps arf2, anticorps arf-1, anticorps MGC52573, anticorps ADP-RIBOSYLATION FACTOR, anticorps ADP-RIBOSYLATION FACTOR 1A, anticorps ADP-ribosylation factor 1, anticorps ATARF, anticorps ATARF1, anticorps ATARFA1A, anticorps F28C11.12, anticorps ARF1, anticorps arf1, anticorps ADP ribosylation factor 1, anticorps ADP-ribosylation factor 1, anticorps ADP ribosylation factor 1 L homeolog, anticorps ADP ribosylation factor 5 L homeolog, anticorps ADP ribosylation factor 1 pseudogene, anticorps adp-ribosylation factor 1, anticorps ARF1, anticorps Arf1, anticorps arf1, anticorps arf1.L, anticorps arf5.L, anticorps NCU08340, anticorps TRIADDRAFT_63238, anticorps PAAG_08805, anticorps LOC100280562, anticorps LOC100280918, anticorps LOC474591, anticorps CLUG_01013

Sujet:

Background: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

Aliases: ADP Ribosylation Factor 1 antibody, ADP-ribosylation factor 1 antibody, ARF 1 antibody, ARF1 antibody, ARF1_HUMAN antibody

UniProt: P84077

Pathways: Transition Metal Ion Homeostasis, Inositol Metabolic Process