ASIP anticorps (AA 23-112) (Biotin)

N° du produit ABIN7143598

Détail du produit anti-ASIP anticorps (Biotin)

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Épitope: AA 23-112

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIP est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Agouti-signaling protein (23-112AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ASIP

Antigène: ASIP (Agouti Signaling Protein (ASIP))

Autre désignation: ASIP (ASIP Produits)

Sujet:

Background: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

Aliases: ASIP antibody, AGTI antibody, AGTIL antibody, ASP antibody, Agouti-signaling protein antibody, ASP antibody, Agouti switch protein antibody

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour