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ASIP anticorps (AA 23-112) (Biotin)

ASIP Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7143598
  • Antigène Voir toutes ASIP Anticorps
    ASIP (Agouti Signaling Protein (ASIP))
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 23-112
    Reactivité
    • 21
    • 2
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASIP est conjugé à/à la Biotin
    Application
    • 11
    • 5
    • 5
    • 4
    • 2
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Agouti-signaling protein (23-112AA)
    Isotype
    IgG
    Top Product
    Discover our top product ASIP Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    ASIP (Agouti Signaling Protein (ASIP))
    Autre désignation
    ASIP (ASIP Produits)
    Sujet

    Background: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

    Aliases: ASIP antibody, AGTI antibody, AGTIL antibody, ASP antibody, Agouti-signaling protein antibody, ASP antibody, Agouti switch protein antibody

    UniProt
    P42127
    Pathways
    Cell-Cell Junction Organization, Feeding Behaviour
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