alpha 2 Macroglobulin anticorps (AA 1216-1467)

N° du produit ABIN7143790

Détail du produit anti-alpha 2 Macroglobulin anticorps

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Épitope: AA 1216-1467

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha 2 Macroglobulin est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Alpha-2-macroglobulin protein (1216-1467AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur alpha 2 Macroglobulin

Antigène: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Autre désignation: A2M (A2M Produits)

Sujet:

Background: Is able to inhibit all four classes of proteinases by a unique \'trapping\' mechanism. This protein has a peptide stretch, called the \'bait region\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Aliases: A2m antibody, A2MG_HUMAN antibody, Alpha 2 M antibody, Alpha 2M antibody, Alpha-2-M antibody, Alpha-2-macroglobulin antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 antibody, CPAMD5 antibody, DKFZp779B086 antibody, FWP007 antibody, S863 7 antibody

UniProt: P01023

Pathways: Lipid Metabolism