Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) anticorps

N° du produit ABIN7143948

Détail du produit

Antigène: Chromosome 6 Open Reading Frame 134 (C6orf134)

Épitope: AA 194-238

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Chromosome 6 Open Reading Frame 134 (C6orf134)

Autre désignation: ATAT1 (C6orf134 Produits)

Synonymes: anticorps C6orf134, anticorps MEC17, anticorps Nbla00487, anticorps TAT, anticorps mec17, anticorps wu:fj19c03, anticorps zgc:65893, anticorps zgc:77443, anticorps Alpha-TAT, anticorps c6orf134, anticorps C23H6orf134, anticorps 0610011P08Rik, anticorps 2610008K08Rik, anticorps 2610110G12Rik, anticorps 3110080J08Rik, anticorps Mec17, anticorps RGD1303066, anticorps C7H6ORF134, anticorps C4H6orf134, anticorps alpha tubulin acetyltransferase 1, anticorps alpha tubulin acetyltransferase 1 S homeolog, anticorps ATAT1, anticorps atat1, anticorps atat1.S, anticorps Atat1

Sujet:

Background: Specifically acetylates \'Lys-40\' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics, this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.

Aliases: Acetyltransferase mec 17 homolog antibody, Acetyltransferase mec-17 homolog antibody, Alpha TAT antibody, Alpha tubulin acetyltransferase 1 antibody, Alpha tubulin N acetyltransferase antibody, Alpha-TAT antibody, Alpha-tubulin N-acetyltransferase antibody, ATAT_HUMAN antibody, ATAT1 antibody, Chromosome 6 open reading frame 134 antibody, Hypothetical protein LOC79969 antibody, MEC17 antibody, Nbla00487 antibody, TAT antibody

UniProt: Q5SQI0