AIMP1 anticorps (AA 25-180)

N° du produit ABIN7143994

Détail du produit anti-AIMP1 anticorps

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Épitope: AA 25-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (25-180AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: AIMP1 (AIMP1 Produits)

Sujet:

Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

Aliases: AIMP 1 antibody, Aimp1 antibody, AIMP1/p43 antibody, AIMP1_HUMAN antibody, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody, ARS interacting multifunctional protein 1 antibody, EMAP 2 antibody, EMAP-2 antibody, EMAP-II antibody, EMAP2 antibody, EMAPII antibody, Endothelial monocyte activating polypeptide 2 antibody, Endothelial monocyte activating polypeptide antibody, Endothelial monocyte-activating polypeptide 2 antibody, Endothelial monocyte-activating polypeptide II antibody, HLD3 antibody, Multisynthase complex auxiliary component p43 antibody, Multisynthetase complex auxiliary component p43 antibody, OTTHUMP00000219673 antibody, p43 antibody, Scye 1 antibody, Scye1 antibody, Scye1, formerly antibody, Small inducible cytokine subfamily E member 1 antibody, Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody, Small inducible cytokine subfamily E, member 1, formerly antibody

UniProt: Q12904