ANAPC2 anticorps (AA 1-230)

N° du produit ABIN7144072

Détail du produit anti-ANAPC2 anticorps

Antigène: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Épitope: AA 1-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Anaphase-promoting complex subunit 2 protein (1-230AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ANAPC2

Antigène: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Autre désignation: ANAPC2 (ANAPC2 Produits)

Synonymes: anticorps anapc2, anticorps ANAPC2, anticorps DDBDRAFT_0203816, anticorps DDBDRAFT_0234264, anticorps DDB_0203816, anticorps DDB_0234264, anticorps si:ch73-203i15.5, anticorps APC2, anticorps RP11-350O14.5, anticorps 9230107K09Rik, anticorps AL024279, anticorps Apc2, anticorps Emi4, anticorps Imi4, anticorps mKIAA1406, anticorps F28I8.30, anticorps F28I8_30, anticorps anaphase-promoting complex/cyclosome 2, anticorps anaphase promoting complex subunit 2, anticorps anaphase promoting complex subunit 2 L homeolog, anticorps anaphase-promoting complex/cyclosome 2, anticorps Anaphase-promoting complex subunit 2, anticorps ANAPC2, anticorps anapc2.L, anticorps anapc2, anticorps Anapc2, anticorps APC2, anticorps apc-2

Sujet:

Background: Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of \\\'Lys-11\\\'-linked polyubiquitin chains and, to a lower extent, the formation of \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.

Aliases: anapc2 antibody, Anaphase promoting complex subunit 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANC2_HUMAN antibody, APC2 antibody, Cyclosome subunit 2 antibody, KIAA1406 antibody, OTTHUMP00000022692 antibody, RP11 350O14.5 antibody

UniProt: Q9UJX6

Pathways: Regulation of Cell Size