ALOX12B anticorps (AA 484-663) (Biotin)
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- Antigène Voir toutes ALOX12B Anticorps
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
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Épitope
- AA 484-663
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALOX12B est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Arachidonate 12-lipoxygenase, 12R-type protein (484-663AA)
- Isotype
- IgG
- Top Product
- Discover our top product ALOX12B Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ALOX12B (Arachidonate 12-Lipoxygenase, 12R Type (ALOX12B))
- Autre désignation
- ALOX12B (ALOX12B Produits)
- Synonymes
- anticorps ALOX12B, anticorps MGC107915, anticorps MGC85124, anticorps 12R-LOX, anticorps ARCI2, anticorps Aloxe2, anticorps e-LOX2, anticorps arachidonate 12-lipoxygenase, 12R type, anticorps arachidonate 12-lipoxygenase, 12R type S homeolog, anticorps ALOX12B, anticorps alox12b, anticorps alox12b.S, anticorps Alox12b
- Sujet
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Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.
Aliases: ALOX12B antibody, Arachidonate 12-lipoxygenase antibody, 12R-type antibody, 12R-LOX antibody, 12R-lipoxygenase antibody, EC 1.13.11.- antibody, Epidermis-type lipoxygenase 12 antibody
- UniProt
- O75342
- Pathways
- Cell-Cell Junction Organization
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