ALOX12 anticorps (AA 508-658) (HRP)
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- Antigène Voir toutes ALOX12 Anticorps
- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
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Épitope
- AA 508-658
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ALOX12 est conjugé à/à la HRP
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)
- Isotype
- IgG
- Top Product
- Discover our top product ALOX12 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))
- Autre désignation
- ALOX12 (ALOX12 Produits)
- Synonymes
- anticorps 15-LOX-1, anticorps 15LOX-1, anticorps 12-LOX, anticorps 12S-LOX, anticorps LOG12, anticorps ALOX12, anticorps ALOX15, anticorps 9930022G08Rik, anticorps Alox12p, anticorps P-12LO, anticorps 12-LO, anticorps zgc:64120, anticorps wu:fb72a11, anticorps arachidonate 15-lipoxygenase, anticorps arachidonate 12-lipoxygenase, 12S type, anticorps arachidonate 12-lipoxygenase, anticorps arachidonate 12-lipoxygenase, 12S-type, anticorps ALOX15, anticorps ALOX12, anticorps Alox12, anticorps alox12, anticorps LOC100072916
- Sujet
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Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.
Aliases: 12 LOX antibody, 12(S) lipoxygenase antibody, 12-lipoxygenase antibody, 12LO antibody, 12S LOX antibody, 12S-lipoxygenase antibody, 12S-LOX antibody, 12S-type antibody, Alox12 antibody, Arachidonate 12 lipoxygenase antibody, Arachidonate 12 lipoxygenase, 12S type antibody, Arachidonate 12-lipoxygenase antibody, Arachidonate 12-oxidoreductase antibody, Lipoxin synthase 12-LO antibody, LOG12 antibody, LOX12_HUMAN antibody, P-12LO antibody, Platelet 12-LOX antibody, Platelet type lipoxygenase 12 antibody, platelet-type 12-lipoxygenase antibody, Platelet-type lipoxygenase 12 antibody
- UniProt
- P18054
- Pathways
- Positive Regulation of Endopeptidase Activity
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