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Asporin anticorps (AA 33-380)

ASPN Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7144761
  • Antigène Voir toutes Asporin (ASPN) Anticorps
    Asporin (ASPN)
    Épitope
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-380
    Reactivité
    • 31
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 28
    • 3
    • 1
    Lapin
    Clonalité
    • 31
    • 1
    Polyclonal
    Conjugué
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Asporin est non-conjugé
    Application
    • 21
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain, Souris
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Asporin protein (33-380AA)
    Isotype
    IgG
    Top Product
    Discover our top product ASPN Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Asporin (ASPN)
    Autre désignation
    ASPN (ASPN Produits)
    Synonymes
    anticorps OS3, anticorps PLAP-1, anticorps PLAP1, anticorps SLRR1C, anticorps bgl3, anticorps aspnl, anticorps wu:fk08c11, anticorps zgc:109936, anticorps 4631401G09Rik, anticorps AA986886, anticorps Plap1, anticorps Slrr1c, anticorps os3, anticorps plap-1, anticorps plap1, anticorps slrr1c, anticorps asporin, anticorps asporin (LRR class 1), anticorps asporin L homeolog, anticorps ASPN, anticorps aspn, anticorps Aspn, anticorps aspn.L
    Sujet

    Background: Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity). Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.

    Aliases: ASPN antibody, ASPN protein antibody, ASPN_HUMAN antibody, Asporin (LRR class 1) antibody, Asporin antibody, Asporin proteoglycan antibody, FLJ20129 antibody, LRR class 1 antibody, Periodontal ligament associated protein 1 antibody, Periodontal ligament-associated protein 1 antibody, PLAP 1 antibody, PLAP-1 antibody, PLAP1 antibody, SLRR 1C antibody, SLRR1C antibody, Small leucine rich protein 1C antibody

    UniProt
    Q9BXN1
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