ARID1A anticorps (AA 655-816) (Biotin)

N° du produit ABIN7144776

Détail du produit anti-ARID1A anticorps (Biotin)

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Épitope: AA 655-816

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARID1A est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human AT-rich interactive domain-containing protein 1A protein (655-816AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARID1A

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Autre désignation: ARID1A (ARID1A Produits)

Synonymes: anticorps B120, anticorps BAF250, anticorps BAF250a, anticorps BM029, anticorps C1orf4, anticorps ELD, anticorps MRD14, anticorps OSA1, anticorps P270, anticorps SMARCF1, anticorps hELD, anticorps hOSA1, anticorps 1110030E03Rik, anticorps Osa1, anticorps Smarcf1, anticorps ARID1A, anticorps wu:fb79b07, anticorps wu:fb95g08, anticorps zgc:171438, anticorps AT-rich interaction domain 1A, anticorps AT rich interactive domain 1A (SWI-like), anticorps AT rich interactive domain 1Aa (SWI-like), anticorps ARID1A, anticorps Arid1a, anticorps arid1a, anticorps arid1aa

Sujet:

Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: actin-dependent regulator of chromatin subfamily F member 1 antibody, ARI1A_HUMAN antibody, ARID domain containing protein 1A antibody, ARID domain-containing protein 1A antibody, ARID1A antibody, AT rich interactive domain 1A (SWI like) antibody, AT rich interactive domain 1A antibody, AT rich interactive domain containing protein 1A antibody, AT-rich interactive domain-containing protein 1A antibody, B120 antibody, BAF250 antibody, BAF250A antibody, BM029 antibody, brain protein 120 antibody, BRG1 associated factor 250 antibody, BRG1 associated factor 250a antibody, BRG1-associated factor 250 antibody, BRG1-associated factor 250a antibody, C1ORF4 antibody, chromatin remodeling factor p250 antibody, chromosome 1 open reading frame 4 antibody, ELD antibody, hELD antibody, hOSA1 antibody, matrix-associated antibody, MRD14 antibody, Osa homolog 1 antibody, OSA1 antibody, OSA1 nuclear protein antibody, P270 antibody, SMARCF1 antibody, SWI like protein antibody, SWI SNF complex protein p270 antibody, SWI-like protein antibody, SWI/SNF complex protein p270 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1 antibody, SWI/SNF-related antibody

UniProt: O14497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation