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PIF1 anticorps (AA 125-360)

PIF1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7144964
  • Antigène Voir toutes PIF1 Anticorps
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    Épitope
    • 4
    • 1
    • 1
    AA 125-360
    Reactivité
    • 13
    • 3
    • 2
    Humain
    Hôte
    • 13
    Lapin
    Clonalité
    • 13
    Polyclonal
    Conjugué
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PIF1 est non-conjugé
    Application
    • 6
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    Autre désignation
    PIF1 (PIF1 Produits)
    Synonymes
    anticorps C15orf20, anticorps PIF, anticorps 4631410M14, anticorps AI449441, anticorps cb934, anticorps fe11d03, anticorps wu:fe11d03, anticorps zgc:56161, anticorps PIF1 5'-to-3' DNA helicase, anticorps PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae), anticorps PIF1, anticorps Pif1, anticorps pif1.L, anticorps pif1
    Sujet

    Background: DNA-dependent ATPase and 5\\\'-3\\\' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.

    Aliases: ATP dependent DNA helicase PIF1 antibody, ATP-dependent DNA helicase PIF1 antibody, C15orf20 antibody, DNA helicase homolog PIF1 antibody, DNA helicase PIF1 antibody, DNA repair and recombination helicase PIF1 antibody, Petite integration frequency 1 antibody, PIF antibody, PIF1 5' to 3' DNA helicase antibody, PIF1 5' to 3' DNA helicase homolog antibody, PIF1 antibody, PIF1 DNA helicase antibody, PIF1/RRM3 DNA helicase like protein antibody, PIF1/RRM3 DNA helicase-like protein antibody, PIF1_HUMAN antibody

    UniProt
    Q9H611
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