PIF1 anticorps (AA 125-360) (Biotin)

N° du produit ABIN7144965

Détail du produit anti-PIF1 anticorps (Biotin)

Antigène: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Épitope: AA 125-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIF1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PIF1

Antigène: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Autre désignation: PIF1 (PIF1 Produits)

Synonymes: anticorps C15orf20, anticorps PIF, anticorps 4631410M14, anticorps AI449441, anticorps cb934, anticorps fe11d03, anticorps wu:fe11d03, anticorps zgc:56161, anticorps PIF1 5'-to-3' DNA helicase, anticorps PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae), anticorps PIF1, anticorps Pif1, anticorps pif1.L, anticorps pif1

Sujet:

Background: DNA-dependent ATPase and 5\\\'-3\\\' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.

Aliases: ATP dependent DNA helicase PIF1 antibody, ATP-dependent DNA helicase PIF1 antibody, C15orf20 antibody, DNA helicase homolog PIF1 antibody, DNA helicase PIF1 antibody, DNA repair and recombination helicase PIF1 antibody, Petite integration frequency 1 antibody, PIF antibody, PIF1 5' to 3' DNA helicase antibody, PIF1 5' to 3' DNA helicase homolog antibody, PIF1 antibody, PIF1 DNA helicase antibody, PIF1/RRM3 DNA helicase like protein antibody, PIF1/RRM3 DNA helicase-like protein antibody, PIF1_HUMAN antibody

UniProt: Q9H611