DDX42 anticorps (AA 519-819) (HRP)

N° du produit ABIN7144993

Détail du produit anti-DDX42 anticorps (HRP)

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Épitope: AA 519-819

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX42 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DDX42

Antigène: DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))

Autre désignation: DDX42 (DDX42 Produits)

Synonymes: anticorps im:7148194, anticorps si:dkey-15n1.10, anticorps zgc:111815, anticorps DDX42P, anticorps RHELP, anticorps RNAHP, anticorps SF3b125, anticorps 1810047H21Rik, anticorps AW319508, anticorps AW556242, anticorps B430002H05Rik, anticorps DEAD (Asp-Glu-Ala-Asp) box helicase 42, anticorps DEAD-box helicase 42, anticorps DEAD-box helicase 42 L homeolog, anticorps DEAD (Asp-Glu-Ala-Asp) box polypeptide 42, anticorps ddx42, anticorps DDX42, anticorps Ddx42, anticorps ddx42.L

Sujet:

Background: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.

Aliases: DDX42ATP-dependent RNA helicase DDX42 antibody, EC 3.6.4.13 antibody, DEAD box protein 42 antibody, RNA helicase-like protein antibody, RHELP antibody, RNA helicase-related protein antibody, RNAHP antibody, SF3b DEAD box protein antibody, Splicing factor 3B-associated 125 kDa protein antibody, SF3b125 antibody

UniProt: Q86XP3