DHX36 anticorps (AA 68-181)

N° du produit ABIN7145003

Détail du produit anti-DHX36 anticorps

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Épitope: AA 68-181

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX36 est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DHX36

Antigène: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Autre désignation: DHX36 (DHX36 Produits)

Synonymes: anticorps DHX57, anticorps DDX36, anticorps G4R1, anticorps MLEL1, anticorps RHAU, anticorps 2810407E23Rik, anticorps AI452301, anticorps AU022184, anticorps Ddx36, anticorps mKIAA1488, anticorps DEAH-box helicase 36, anticorps ATP-dependent RNA helicase DHX36, anticorps DEAH (Asp-Glu-Ala-His) box polypeptide 36, anticorps Dhx36, anticorps DHX36, anticorps dhx36, anticorps LOC100456222, anticorps LOC100633205

Sujet:

Background: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5\'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5\'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3\'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

Aliases: DDX36 antibody, DEAH box protein 36 antibody, Dhx36 antibody, DHX36_HUMAN antibody, EC 3.6.1.- antibody, KIAA1488 antibody, MLE like protein 1 antibody, MLE-like protein 1 antibody, MLEL1 antibody, Probable ATP dependent RNA helicase DHX36 antibody, Probable ATP-dependent RNA helicase DHX36 antibody, RHAU antibody, RNA helicase associated with AU rich element ARE antibody, RNA helicase associated with AU-rich element ARE antibody

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades