Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

BBS7 anticorps (AA 289-393) (Biotin)

BBS7 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7145247
  • Antigène Voir toutes BBS7 Anticorps
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Épitope
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 289-393
    Reactivité
    • 30
    • 3
    • 2
    Humain
    Hôte
    • 26
    • 3
    • 1
    Lapin
    Clonalité
    • 28
    • 2
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 2
    • 2
    • 2
    Cet anticorp BBS7 est conjugé à/à la Biotin
    Application
    • 26
    • 19
    • 3
    • 3
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Bardet-Biedl syndrome 7 protein (289-393AA)
    Isotype
    IgG
    Top Product
    Discover our top product BBS7 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Autre désignation
    BBS7 (BBS7 Produits)
    Synonymes
    anticorps BBS7, anticorps bbs2l1, anticorps BBS2L1, anticorps id:ibd5048, anticorps zgc:153772, anticorps 8430406N16Rik, anticorps Bardet-Biedl syndrome 7, anticorps bardet-biedl syndrome 7, anticorps Bardet-Biedl syndrome 7 L homeolog, anticorps Bardet-Biedl syndrome 7 (human), anticorps BBS7, anticorps bbs7, anticorps MICPUN_100192, anticorps MICPUCDRAFT_16331, anticorps bbs7.L, anticorps Bbs7
    Sujet

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.

    Aliases: Bardet Biedl syndrome 7 protein antibody, Bardet-Biedl syndrome 7 antibody, Bardet-Biedl syndrome 7 protein antibody, BBS2 like 1 antibody, BBS2 like protein 1 antibody, BBS2-like protein 1 antibody, BBS2L1 antibody, BBS7 antibody, BBS7_HUMAN antibody, FLJ10715 antibody

    UniProt
    Q8IWZ6
    Pathways
    Signalisation Hedgehog
Vous êtes ici:
Support technique