DEFB126 anticorps (AA 36-111) (Biotin)

N° du produit ABIN7145481

Détail du produit anti-DEFB126 anticorps (Biotin)

Antigène: DEFB126 (Defensin, beta 126 (DEFB126))

Épitope: AA 36-111

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEFB126 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Beta-defensin 126 protein (36-111AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DEFB126

Antigène: DEFB126 (Defensin, beta 126 (DEFB126))

Autre désignation: DEFB126 (DEFB126 Produits)

Synonymes: anticorps C20orf8, anticorps DEFB-26, anticorps DEFB26, anticorps bA530N10.1, anticorps hBD-26, anticorps ESP13.2, anticorps esp13.2, anticorps defensin beta 126, anticorps DEFB126

Sujet:

Background: Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection, both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte (By similarity). In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (PubMed:19373462, PubMed:23229569).

Aliases: DEFB126 antibody, C20orf8 antibody, DEFB26Beta-defensin 126 antibody, Beta-defensin 26 antibody, DEFB-26 antibody, Defensin antibody, beta 126 antibody, Epididymal secretory protein 13.2 antibody, ESP13.2 antibody, HBD26 antibody

UniProt: Q9BYW3