EPRS anticorps (AA 1207-1399)

N° du produit ABIN7145566

Détail du produit anti-EPRS anticorps

Antigène: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Épitope: AA 1207-1399

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPRS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Bifunctional glutamate/proline--tRNA ligase protein (1207-1399AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EPRS

Antigène: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Autre désignation: EPRS (EPRS Produits)

Synonymes: anticorps EARS, anticorps GLUPRORS, anticorps PARS, anticorps QARS, anticorps QPRS, anticorps wu:fb38d08, anticorps wu:ft34d10, anticorps 2410081F06Rik, anticorps 3010002K18Rik, anticorps C79379, anticorps Qprs, anticorps glutamyl-prolyl-tRNA synthetase, anticorps glutamyl-prolyl-tRNA synthetase S homeolog, anticorps EPRS, anticorps eprs, anticorps eprs.S, anticorps Eprs

Sujet:

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\\\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Aliases: Bifunctional aminoacyl tRNA synthetase antibody, Bifunctional aminoacyl-tRNA synthetase antibody, Bifunctional glutamate/proline tRNA ligase antibody, Cell proliferation-inducing gene 32 protein antibody, DKFZp313B047 antibody, EARS antibody, Eprs antibody, GLNS antibody, Glu pro tRNA synthetase antibody, GLUPRORS antibody, GluRS antibody, Glutamate tRNA ligase antibody, Glutamatyl prolyl tRNA synthetase antibody, Glutaminyl tRNA synthetase antibody, Glutamyl prolyl tRNA synthetase antibody, Glutamyl tRNA synthetase antibody, Glutamyl-tRNA synthetase antibody, PARS antibody, PIG 32 antibody, PIG32 antibody, Proliferation inducing gene 32 protein antibody, Proliferation inducing protein 32 antibody, Proline tRNA ligase antibody, Proline--tRNA ligase antibody, Prolyl tRNA synthetase antibody, Prolyl-tRNA synthetase antibody, QARS antibody, QPRS antibody, SYEP_HUMAN antibody

UniProt: P07814