BRD7 anticorps (AA 601-651)

N° du produit ABIN7145816

Détail du produit anti-BRD7 anticorps

Antigène: BRD7 (Bromodomain Containing 7 (BRD7))

Épitope: AA 601-651

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRD7 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BRD7

Antigène: BRD7 (Bromodomain Containing 7 (BRD7))

Autre désignation: BRD7 (BRD7 Produits)

Synonymes: anticorps zgc:66347, anticorps wu:fc95f02, anticorps MGC79478, anticorps BRD7, anticorps BP75, anticorps CELTIX1, anticorps NAG4, anticorps Ptpn13ip, anticorps bromodomain containing 7 L homeolog, anticorps bromodomain containing 7, anticorps brd7.L, anticorps brd7, anticorps BRD7, anticorps Brd7

Sujet:

Background: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.

Aliases: 75 kDa bromodomain protein antibody, BP75 antibody, BRD 7 antibody, BRD7 antibody, BRD7_HUMAN antibody, Bromodomain containing 7 antibody, bromodomain containing protein 7 antibody, Bromodomain-containing protein 7 antibody, CELTIX 1 antibody, CELTIX1 antibody, NAG4 antibody, Protein CELTIX-1 antibody

UniProt: Q9NPI1