CXCR4 anticorps (AA 1-356)

N° du produit ABIN7146107

Détail du produit anti-CXCR4 anticorps

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Épitope: AA 1-356

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human C-X-C chemokine receptor type 4 protein (1-356AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4 (CXCR4 Produits)

Sujet:

Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Aliases: C-X-C chemokine receptor type 4 antibody, CD184 antibody, CD184 antigen antibody, Chemokine (C X C motif) receptor 4 antibody, Chemokine CXC Motif Receptor 4 antibody, CXC-R4 antibody, CXCR-4 antibody, CXCR4 antibody, CXCR4_HUMAN antibody, D2S201E antibody, FB22 antibody, Fusin antibody, HM89 antibody, HSY3RR antibody, LAP 3 antibody, LAP3 antibody, LCR1 antibody, LESTR antibody, Leukocyte derived seven transmembrane domain receptor antibody, Leukocyte-derived seven transmembrane domain receptor antibody, Lipopolysaccharide associated protein 3 antibody, Neuropeptide Y receptor Y3 antibody, NPY3R antibody, NPYR antibody, NPYRL antibody, NPYY3 antibody, NPYY3R antibody, Probable G protein coupled receptor lcr1 homolog antibody, SDF 1 receptor antibody, SDF-1 receptor antibody, SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody, Stromal cell derived factor 1 receptor antibody, Stromal cell-derived factor 1 receptor antibody, WHIM antibody, WHIMS antibody

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events