ORAI1 anticorps (AA 1-87)

N° du produit ABIN7146306

Détail du produit anti-ORAI1 anticorps

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Épitope: AA 1-87

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORAI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Calcium release-activated calcium channel protein 1 protein (1-87AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ORAI1

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Autre désignation: ORAI1 (ORAI1 Produits)

Synonymes: anticorps CRACM1, anticorps ORAT1, anticorps TMEM142A, anticorps RGD1311873, anticorps D730049H07Rik, anticorps Tmem142a, anticorps orai-1, anticorps im:7146264, anticorps orai1, anticorps tmem142a, anticorps zgc:109721, anticorps orai2, anticorps ORAI1, anticorps LOC100218031, anticorps ORAI calcium release-activated calcium modulator 1, anticorps ORAI calcium release-activated calcium modulator 1b, anticorps ORAI calcium release-activated calcium modulator 1 S homeolog, anticorps ORAI1, anticorps Orai1, anticorps orai1b, anticorps orai1.S, anticorps orai1

Sujet:

Background: Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).

Aliases: Calcium release activated calcium channel protein 1 antibody, Calcium release activated calcium modulator 1 antibody, Calcium release-activated calcium channel protein 1 antibody, CRACM 1 antibody, CRACM1 antibody, CRCM1 antibody, CRCM1_HUMAN antibody, FLJ14466 antibody, Orai 1 antibody, ORAI calcium release activated calcium modulator 1 antibody, orai1 antibody, ORAT1 antibody, Protein orai 1 antibody, Protein orai-1 antibody, TMEM 142A antibody, TMEM142A antibody, Transmembrane protein 142A antibody

UniProt: Q96D31

Pathways: TCR Signaling, BCR Signaling