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EFHA1 anticorps (AA 26-247)

EFHA1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7146326
  • Antigène Voir toutes EFHA1 Anticorps
    EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
    Épitope
    • 4
    • 2
    • 1
    AA 26-247
    Reactivité
    • 24
    • 17
    • 17
    Humain
    Hôte
    • 22
    • 2
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EFHA1 est non-conjugé
    Application
    • 19
    • 13
    • 4
    • 3
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Calcium uptake protein 2, mitochondrial protein (26-247AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
    Autre désignation
    MICU2 (EFHA1 Produits)
    Sujet

    Background: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).

    Aliases: 1110008L20Rik antibody, EF hand domain containing family member A1 antibody, EF hand domain family A1 antibody, EF hand domain family member A1 antibody, EF-hand domain-containing family member A1 antibody, EFHA1 antibody, EFHA1 EF hand domain family member A1 antibody, EFHA1_HUMAN antibody, FLJ25016 antibody, FLJ34588 antibody, Smhs2 homolog antibody

    UniProt
    Q8IYU8
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