SS18L1 anticorps (AA 47-396)

N° du produit ABIN7146400

Détail du produit anti-SS18L1 anticorps

Antigène: SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))

Épitope: AA 47-396

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SS18L1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Calcium-responsive transactivator protein (47-396AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SS18L1

Antigène: SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))

Autre désignation: SS18L1 (SS18L1 Produits)

Synonymes: anticorps crest, anticorps CREST, anticorps LP2261, anticorps A230053O16Rik, anticorps SS18L1, nBAF chromatin remodeling complex subunit, anticorps synovial sarcoma translocation gene on chromosome 18-like 1, anticorps synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog, anticorps SS18, nBAF chromatin remodeling complex subunit like 1, anticorps SS18L1, anticorps ss18l1, anticorps ss18l1.S, anticorps Ss18l1

Sujet:

Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).

Aliases: Calcium-responsive transactivator antibody, CREST antibody, CREST_HUMAN antibody, KIAA0693 antibody, LP2261 antibody, MGC26711 antibody, MGC78386 antibody, sarcoma translocation gene on chromosome18like1 antibody, SS18 antibody, SS18-like protein 1 antibody, SS18L1 antibody, SS18L1 nBAF chromatin remodeling complex antibody, SSXT antibody, synovial sarcoma translocation antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, SYT homolog 1 antibody

UniProt: O75177