Casein Kinase 1 gamma 2 anticorps (Isoform gamma 2)
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- Antigène Voir toutes Casein Kinase 1 gamma 2 (CSNK1G2) Anticorps
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
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Épitope
- AA 316-415, Isoform gamma 2
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Casein Kinase 1 gamma 2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Réactivité croisée
- Humain, Souris
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Casein kinase I isoform gamma-2 protein (316-415AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- Casein Kinase 1 gamma 2 (CSNK1G2) (Casein Kinase 1, gamma 2 (CSNK1G2))
- Autre désignation
- CSNK1G2 (CSNK1G2 Produits)
- Synonymes
- anticorps CK1g2, anticorps 2810429I12Rik, anticorps AI463719, anticorps CKI, anticorps ck1-gamma, anticorps CSNK1G2, anticorps ck1g2, anticorps csnk1g2, anticorps fj97g11, anticorps wu:fj97g11, anticorps wz8345, anticorps zgc:110719, anticorps zgc:153415, anticorps casein kinase 1 gamma 2, anticorps casein kinase 1, gamma 2, anticorps casein kinase 1 gamma 2 L homeolog, anticorps casein kinase 1, gamma 2a, anticorps casein kinase 1, gamma 2b, anticorps CSNK1G2, anticorps Csnk1g2, anticorps csnk1g2.L, anticorps csnk1g2, anticorps csnk1g2a, anticorps csnk1g2b
- Sujet
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Background: Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
Aliases: Casein kinase 1, gamma 2 antibody, Casein kinase I isoform gamma 2 antibody, Casein kinase I isoform gamma-2 antibody, CK1g2 antibody, CKI gamma 2 antibody, CKI-gamma 2 antibody, CSNK1G 2 antibody, Csnk1g2 antibody, KC1G2_HUMAN antibody
- UniProt
- P78368
- Pathways
- Signalisation Hedgehog
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