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CARD16 anticorps (AA 1-197)

CARD16 Reactivité: Humain ELISA, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7146911
  • Antigène Voir toutes CARD16 Anticorps
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    Épitope
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-197
    Reactivité
    Humain
    Hôte
    • 21
    • 4
    • 1
    Lapin
    Clonalité
    • 24
    • 2
    Polyclonal
    Conjugué
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CARD16 est non-conjugé
    Application
    • 16
    • 12
    • 9
    • 3
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)
    Isotype
    IgG
    Top Product
    Discover our top product CARD16 Anticorps primaire
  • Indications d'application
    Recommended dilution: IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
    Autre désignation
    CARD16 (CARD16 Produits)
    Synonymes
    anticorps COP, anticorps COP1, anticorps PSEUDO-ICE, anticorps caspase recruitment domain family member 16, anticorps CARD16
    Sujet

    Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

    Aliases: CAR16_HUMAN antibody, CARD only domain-containing protein 1 antibody, CARD only protein antibody, CARD16 antibody, Caspase recruitment domain family, member 16 antibody, Caspase recruitment domain-containing protein 16 antibody, Caspase-1 dominant-negative inhibitor pseudo-ICE antibody, Caspase-1 inhibitor COP antibody, COP antibody, COP1 antibody, Pseudo interleukin 1 beta converting enzyme antibody, Pseudo interleukin-1 beta converting enzyme antibody, Pseudo interleukin-1beta converting enzyme antibody, PSEUDO-ICE antibody

    UniProt
    Q5EG05
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