CATSPER4 anticorps (AA 306-472)

N° du produit ABIN7147035

Détail du produit anti-CATSPER4 anticorps

Antigène: CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))

Épitope: AA 306-472

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CATSPER4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CATSPER4

Antigène: CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))

Autre désignation: CATSPER4 (CATSPER4 Produits)

Synonymes: anticorps RGD1565213, anticorps 4933412L05, anticorps cation channel, sperm associated 4, anticorps cation channel sperm associated 4, anticorps Catsper4, anticorps CATSPER4

Sujet:

Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody

UniProt: Q7RTX7