CNOT3 anticorps (AA 257-395)

N° du produit ABIN7147101

Détail du produit anti-CNOT3 anticorps

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Épitope: AA 257-395

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human CCR4-NOT transcription complex subunit 3 protein (257-395AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CNOT3

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Autre désignation: CNOT3 (CNOT3 Produits)

Synonymes: anticorps LENG2, anticorps NOT3, anticorps NOT3H, anticorps A930039N10Rik, anticorps cnot3, anticorps zgc:55934, anticorps wu:fi20g07, anticorps fb73b06, anticorps fc17h07, anticorps wu:fb73b06, anticorps wu:fc17h07, anticorps zgc:92813, anticorps CNOT3, anticorps Afu2g02070, anticorps AO090011000479, anticorps CG8426, anticorps Dmel\\CG8426, anticorps NOT3.5, anticorps NOT3/5, anticorps Not3, anticorps not3, anticorps not3/5, anticorps leng2, anticorps not3h, anticorps CCR4-NOT transcription complex subunit 3, anticorps CCR4-NOT transcription complex, subunit 3, anticorps CCR4-NOT transcription complex, subunit 3b, anticorps CCR4-NOT transcription complex, subunit 3a, anticorps CCR4-NOT transcription complex subunit 3 S homeolog, anticorps CNOT3, anticorps Cnot3, anticorps cnot3b, anticorps cnot3a, anticorps AFUA_2G02070, anticorps NFIA_034440, anticorps ACLA_092760, anticorps PMAA_089540, anticorps AFLA_043060, anticorps TSTA_125290, anticorps ANI_1_738064, anticorps AOR_1_812054, anticorps Not3, anticorps cnot3, anticorps cnot3.S

Sujet:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity.

Aliases: CCR4 associated factor 3 antibody, CCR4-associated factor 3 antibody, CCR4-NOT transcription complex subunit 3 antibody, CNOT3 antibody, CNOT3_HUMAN antibody, KIAA0691 antibody, LENG2 antibody, Leukocyte receptor cluster member 2 antibody, negative regulator of transcription 3, S. cerevisiae, homolog of antibody, NOT3 (negative regulator of transcription 3, yeast) homolog antibody, NOT3 antibody, NOT3H antibody

UniProt: O75175

Pathways: Stem Cell Maintenance