CD166 anticorps (AA 28-180)

N° du produit ABIN7147123

Détail du produit anti-CD166 anticorps

Antigène: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Épitope: AA 28-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD166 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human CD166 antigen protein (28-180AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CD166

Antigène: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Autre désignation: ALCAM (ALCAM Produits)

Synonymes: anticorps CD166, anticorps MEMD, anticorps ALCAM, anticorps BEN, anticorps DM-GRASP, anticorps JC7, anticorps SC1, anticorps AI853494, anticorps MuSC, anticorps alcam, anticorps cd166, anticorps memd, anticorps fb53h09, anticorps fb80a10, anticorps nlcam, anticorps si:ch211-190h2.4, anticorps wu:fb53h09, anticorps wu:fb80a10, anticorps wu:fc14b01, anticorps activated leukocyte cell adhesion molecule, anticorps activated leukocyte cell adhesion molecule a, anticorps activated leukocyte cell adhesion molecule L homeolog, anticorps CD166 antigen homolog, anticorps activated leukocyte cell adhesion molecule b, anticorps ALCAM, anticorps Alcam, anticorps alcama, anticorps alcam.L, anticorps alcam, anticorps cd166, anticorps alcamb

Sujet:

Background: Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts (PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703, PubMed:16352806, PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938, PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415, PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415, PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis, required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance, axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).

Aliases: Activated leukocyte cell adhesion molecule antibody, ALCAM antibody, ALCAM protein antibody, CD 166 antibody, CD166 antibody, CD166 antigen antibody, CD166_HUMAN antibody, FLJ3851 antibody, FLJ38514 antibody, MEMD antibody, MGC71733 antibody

UniProt: Q13740