CDK5RAP3 anticorps (Regulatory Subunit) (Biotin)
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- Antigène Voir toutes CDK5RAP3 Anticorps
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
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Épitope
- AA 42-292, Regulatory Subunit
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK5RAP3 est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human CDK5 regulatory subunit-associated protein 3 protein (42-292AA)
- Isotype
- IgG
- Top Product
- Discover our top product CDK5RAP3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
- Autre désignation
- CDK5RAP3 (CDK5RAP3 Produits)
- Synonymes
- anticorps cdkrap3, anticorps fb33h04, anticorps fc09c05, anticorps id:ibd2920, anticorps wu:fb33h04, anticorps wu:fc09c05, anticorps zgc:86863, anticorps CDK5RAP3, anticorps cdk5rap3, anticorps MGC82350, anticorps C53, anticorps HSF-27, anticorps IC53, anticorps LZAP, anticorps MST016, anticorps OK/SW-cl.114, anticorps PP1553, anticorps 1810007E24Rik, anticorps BC002318, anticorps C81486, anticorps CDK5 regulatory subunit associated protein 3, anticorps CDK5 regulatory subunit associated protein 3 L homeolog, anticorps cdk5rap3, anticorps CDK5RAP3, anticorps cdk5rap3.L, anticorps Cdk5rap3
- Sujet
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Background: Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation (PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation (PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint (PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation (PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis (PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1 (PubMed:21283629).
Aliases: C53 antibody, CDK5 activator binding protein C53 antibody, CDK5 activator-binding protein C53 antibody, CDK5 regulatory subunit associated protein 3 antibody, CDK5 regulatory subunit-associated protein 3 antibody, Cdk5rap3 antibody, CK5P3_HUMAN antibody, HSF 27 antibody, HSF27 antibody, IC53 antibody, Ischemic heart CDK5 activator binding protein C53 antibody, LXXLL/leucine zipper containing ARFbinding protein antibody, LZAP antibody, MST016 antibody, OK/SW cl.114 antibody, PP1553 antibody, Protein HSF-27 antibody
- UniProt
- Q96JB5
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